The RAPID Sepsis Assessment guidelines below are used at UCSF Benioff Children's Hospital Oakland and are provided only as a reference. They are based on the International Pediatric Sepsis Consensus Conference: Definitions for sepsis and organ dysfunction in pediatrics Pediatric Critical Care Medicine, 2005 Vol. 6, No. 1.
Step 1
Two of the following (one must be TEMP or WBC)
- Temp: > 38.5 or < 36
- WBC: see table below
- RR: see table below
- HR: see table below
If Yes = SIRS (Systemic Inflammatory Response Syndrome)
Step 2
Infection suspected?
If Yes = Sepsis
Step 3
End organ dysfunction?
- Lethargy/irritability/altered mental status (not just "cranky") or
- Poor perfusion (CRT > 3 secs) or
- Decreased urine output (< 0.5 ml/kg/hr) or
- Any bilateral infiltrates on CXR + need for oxygen
If Yes = Severe sepsis
- Call MD (attending physician or PICU attending or fellow) immediately
- Consider sending labs and starting severe sepsis guideline
Step 4
Hypotension?
If Yes = Severe shock
- Start severe sepsis guideline immediately
Age Group |
Tachycardia | Bradycardia | Respiratory Rate | WBC | Systolic BP |
0 day – 1 wk | > 180 | < 100 | > 50 | > 34 | < 65 |
1 wk – 1mo |
> 180 | < 100 | > 40 | > 19.5 or < 5 | < 75 |
1 mo – 24 mo |
> 180 | < 90 | > 34 | > 17.5 or < 5 | < 100 |
2 – 5 yrs |
> 140 | n/a | > 22 | > 15.5 or < 6 | < 94 |
6 – 12 yrs |
> 130 | n/a | > 18 | > 13.5 or < 4.5 | < 105 |
13 – < 18 yrs |
> 110 | n/a | > 14 | > 11 or < 4.5 | < 117 |