I learn something new every day from my patients. They are the best teachers.
Where I see patients (6)
Selected research
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A Phase 1 Study of ABI-009 (Nab-sirolimus) in Combination With Temozolomide and Irinotecan in Pediatric Patients With Recurrent or Refractory Solid Tumors, Including CNS Tumors-A Children's Oncology Group Pediatric Early Phase Clinical Trial Network Study ADVL1514.
Cancer medicine
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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
The Lancet. Oncology
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Functional interactions between neurofibromatosis tumor suppressors underlie Schwann cell tumor de-differentiation and treatment resistance.
Nature communications
Clinical trials
A Study of a New Way to Treat Children and Young Adults With a Brain Tumor Called NGGCT
Will be measured by the number of progressions or deaths within 2 years of enrollment for the cohort treated with whole ventricular + spinal canal irradiation (WVSCI). The final analysis will include an exact binomial confidence i...
Recruiting
More about this studyA Study to See if Memantine Protects the Brain During Radiation Therapy Treatment for Primary C...
We will estimate the difference in mean Cogstate composite Z score slopes (reflecting change in Cogstate composite Z scores from baseline to 12 months post baseline taking into account measurements at those time points as well as ...
Recruiting
More about this studyDabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Dia...
The EFS curve for the new treatment cohort (Stratum 1) will be estimated by Kaplan Meier estimates. A 2-sample, 1 sided log-rank test will be used to test whether the EFS distribution is better in new treatment compared with histo...
Recruiting
More about this studyA Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse I...
Defined as the highest dose of selinexor in combination with standard of care radiation therapy (RT) that does not cause unacceptable side effects.
Recruiting
More about this studyA Study of the Drugs Selumetinib Versus Carboplatin/Vincristine in Patients With Neurofibromato...
EFS is defined as time from randomization to the first occurrence of any of the following events: clinical or radiographic disease progression, disease recurrence, second malignant neoplasm, or death from any cause. Patients who a...
Recruiting
More about this studyA Study of the Drugs Selumetinib vs. Carboplatin and Vincristine in Patients With Low-Grade Gli...
The Kaplan-Meier method will be used to estimate EFS which is defined as the interval from randomization to first occurrence of clinical or radiographic disease progression, disease recurrence, second malignant neoplasm, or death ...
Recruiting
More about this studyStudy of Nivolumab and Ipilimumab in Children and Young Adults With INI1-Negative Cancers
Based on Response Evaluation in Solid Tumors (RECIST) version 1.1
Recruiting
More about this studyContact me
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